Conclusions: Constitutive activation of c‐Abl/PKC‐δ/Fli1 pathway at least partially contributes to the establishment of pro‐fibrotic phenotype in LSc dermal fibroblasts, which provides a novel molecular basis to explain the efficacy of imatinib against skin sclerosis in a certain subset of LSc. (Source: British Journal of Dermatology)
CONCLUSIONS AND IMPLICATIONSAscorbic acid, known to inhibit Cav3.2 channels, suppressed neuropathic hyperalgesia. DI‐VCP ointment for topical application may be of benefit in the treatment of neuropathic pain. (Source: British Journal of Pharmacology)
Conclusions These results suggest that androgens deregulate DPC‐secreted factors involved in normal HF stem cell differentiation via the inhibition of the canonical Wnt signalling pathway. (Source: British Journal of Dermatology)
Conclusions Aquagenic keratoderma may be associated with a heterozygous mutation in the cystic fibrosis gene. Although the diagnosis is a clinical one, histopathology is useful and may reveal some characteristic diagnostic clues.
Conclusions We found four microRNAs that could participate in the pathogenesis of male pattern baldness.
Conclusions: The overall NNE value in pediatric patients over the 10‐year study period was 593,8, meaning that about 594 lesions were excised to find 1 melanoma.
Conclusions: The overall NNE value in pediatric patients over the 10-year study period was 593,8, meaning that about 594 lesions were excised to find 1 melanoma. This value is 20 times higher than the rates found in adult patients
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