Primary cutaneous neuroendocrine carcinoma, also known as Merkel cell carcinoma (MCC), usually presents as a dermal and/or subcutaneous tumor. Rarely, it is confined to the epidermis or adnexal epithelium [MCC in situ (MCCIS)]. Little is known about the spectrum of features and biology of MCCIS.
ConclusionsThickness of the epidermis and dermis is dependent on body region.
Conclusion: Oral administration of CTP improves dry skin and normalizes axon-guidance factors in the epidermis in addition to reducing pruritus. CTP may be used in a new therapeutic strategy against dry skin and pruritus. (Source: Journal of Dermatological Science)
Alcoholism is associated with cutaneous immune deficiency and while the basis for this is largely unknown, the sensitivity of skin immune cells to EtOH has been clearly demonstrated. Murine models of alcoholism have shown that EtOH reduces skin dendritic cell (DC) numbers and compromises their migratory capacity following skin sensitization.
The present study investigated the protective effects of pine bark extract (PBE) against hexavalent chromium [Cr(VI)]‐induced dermatotoxicity in rats. Skin reactions were evaluated by visual inspection, histopathological changes and oxidative stress parameters.
The objective of our work was to identify RCM parameters able to quantify in vivo dermis papilla density and epidermis pigmentation potentially applicable in clinical studies. The study included 111 healthy female volunteers with phototype I to VI.
This study reveals that not only do adult (M ≥ 525 mm, F ≥ 550 mm) S. canicula show a sexual dimorphism in the epidermis and dermis, but that hatchling S. canicula are born with a sexually dimorphic epidermal layer and this persists into the juvenile stage (M
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