Abstract: Glycyrrhizic acid (GA), a triterpenoid saponin glycoside from the roots and rhizomes of licorice is used in traditional and modern medicine for the treatment of numerous medical conditions including skin diseases and beauty care product. In the present study, we investigated the effect of GA against ultraviolet B (UVB) irradiation-induced photoaging in human dermal fibroblasts (HDFs) and its possible mechanism of action. HDFs were subjected to photoaging by sub-toxic dose of UVB (10mj/cm2) irradiation
Authors: Nakajima H, Ezaki Y, Nagai T, Yoshioka R, Imokawa G Abstract We recently reported that overexpression of the elastase NEP (neutral endopeptidase) by fibroblasts plays a pivotal role in the mechanism of UVB-induced skin wrinkling by degrading dermal elastic fibres.
AbstractWe have investigated the expression and role of galectin‐1 and other galectins in psoriasis and in the Th1/Th17 effector and dendritic cell responses associated with this chronic inflammatory skin condition. To determine differences between psoriasis patients and healthy donors, expression of galectins was analysed by RT‐PCR in skin samples and on epidermal and peripheral blood dendritic cells by immunofluorescence and flow cytometry.
The aqueous extracts of Citrus unshiu peel containing flavonoid glycosides was used as co‐substrate with Schizophyllum commune mycelia producing β‐glucosidase and its biological activities were studied. β‐glucosidase‐produced S. commune mycelia converted the glycosides (narirutin and hesperidin) into aglycones (naringenin and hesperetin)
Celebrity Dirty Laundry Cameron Diaz Destroyed By Cosmetic Surgery Gone Wild (Photo) Celebrity Dirty Laundry This appears to be the result of Restylane or Radiesse .” “Her Botox is so overdone she's lost her expression… the mouth area looks frozen. The sheen to her skin is likely from laser treatments such as CO2 laser which would result in this artificial ..
Authors: Alibardi L, Polazzi E Abstract The present study shows the localization of epidermal and dermal proteins produced in lizard skin cultivated in vitro.
Authors: Ostuni A, Infantino V, Salvia A, Miglionico R, Boraldi F, Annovi G, Bisaccia F Abstract Progressive calcification and fragmentation of elastic fibers are characteristic hallmarks of Pseudoxanthoma elasticum (PXE) which is caused by mutations in the ABCC6 gene encoding the multidrug resistance-associated protein 6 (MRP6). Several evidences suggested that PXE is a metabolic disorder but the exact mechanism by which ABCC6 mutations promote the elastic fiber mineralization is unknown.
AbstractWe have investigated the expression and role of galectin‐1 and other galectins in psoriasis and in the Th1/Th17 effector and dendritic cell responses associated with this chronic inflammatory skin condition.
In this study, we examined the role of periostin in the process of cutaneous wound repair using periostin‐deficient mice and by analyzing the effects of periostin on dermal fibroblasts.
Authors: Du J, Zeng C, Li Q, Chen B, Liu H, Huang X, Huang Q Abstract Sphingosine-1-phosphate (S1P) is a bioactive sophospholipid with various S1P receptor (S1PR) expression profiles in cells of different origin. S1PR1, R3 and – to a lesser extent – R2 were the main receptors expressed in most of endothelial cells (ECs). The balances in the expression and activation of S1PR1, R2 and R3 help to maintain the physiological functions of ECs.
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